Browsing by Author "Amr Ehab El-Qushayri"
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- ItemAssociation of anthelmintic treatment with malaria prevalence, incidence, and parasitemia: A systematic review and meta-analysis(2021) Kadek Agus Surya Dila; Ahmed Reda Ahmed; Mohamed Tamer Elhady; Linh Le; Duc Nguyen; Amr Ehab El-Qushayri; Han Nguyen; Varshil Mehta; Walid Mohamed Attiah Hamad; Hany Eskarous; Maryan Samsom; Kenji Hirayama; Huy NguyenA chronic helminth infection can alter host immune response and affect malaria infection. We conducted a systematic review and meta-analysis to find the impact of anthelmintic treatment on malaria prevalence, incidence, and parasitemia. Nine and 12 electronic databases were searched on 28th July 2015 and 26 June 2020 for relevant studies. We performed a meta-analysis for malaria prevalence, incidence, parasitemia, and a qualitative synthesis for other effects of anthelmintic treatment. Seventeen relevant papers were included. There was no association between anthelmintic treatment and malaria prevalence or change of parasitemia at the end of the follow-up period (pooled OR 0.93, 95% CI: 0.62, 1.38, p-value=0.71 and SMD -0.08, 95%CI: -0.24, 0.07, p-value=0.30 respectively) or at any defined time points in the analysis. Pooled analysis of three studies demonstrated no association between malaria incidence and anthelmintic treatment (rate ratio 0.93, 95%CI: 0.80, 1.08, p-value=0.33). Our study encourages anthelmintic treatment in countries with a high burden of co-infections as anthelmintic treatment is not associated with change in malaria prevalence, incidence, or parasitemia.